Competitive Price CAS60-80-0 Antipyrine with Safe and Fast Delivery
Antipyrine is an analgesic, a non-steroidal anti-inflammatory drug and an antipyretic.
Phenazone, also known as phenazon, antipyrine, or analgesine, is an analgesic, a non-steroidal anti-inflammatory drug and an antipyretic. It was first synthesized by Ludwig Knorr in 1883. It is formed by reducing diortho- dinitrodiphenyl with sodium amalgam and methyl alcohol, or by heating diphenylene-ortho-dihydrazine with hydrochloric acid to 150 °C. It crystallizes in needles which melt at 156 °C. Potassium permanganate oxidizes it to pyridazine tetracarboxylic acid. Phenazone has an elimination half life of about 12 hours.
| Product Name |
Antipyrine/Phenazone |
| Synonyms |
1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one; 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one; Phenazone |
| CAS No. |
60-80-0 |
| EINECS |
200-486-6 |
| Molecular Formula |
C11H12N2O |
| Molecular Weight |
188.23 |
| Appearance |
Colorless powder |
| Melting point |
109-113 ºC |
| Item |
Standard |
Result |
| Appearance |
White or primrose yellow crystalline powder |
White crystalline powder |
| Identification |
IR |
Conform |
| Melting point |
109~113°C |
111.5°C |
| Appearance of Solution |
clear and colorless |
Conform |
| Acidity or alkalinity |
complies |
Conform |
| Chloride |
100ppm max |
80ppm |
| Loss on drying |
≤1.0% |
0.01% |
| Residue no Ignition |
≤0.1% |
0.04% |
| Heavy Metals |
≤0.002% |
<0.002% |
| Related compounds |
Meets the requirements |
Conform |
| Assay (on drying) |
99.0~101% |
99.5% |
| Residual solvents(ethanol) |
1000ppm max |
275ppm |
| Related substances |
impurity A |
not detected |
| unspecified impurity0.05%max |
not detected |
| total impurities0.1%max |
not detected |
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