Pharmaceutical API Veterinary Raw Material CAS91832-40-5 Cefdinir

• Varieties: Other
• Component: Chemical Synthetic Drugs
• Type: Other
• Pharmacodynamic Influential Factors: Other
• Storage Method: Prevent Exceeding Quality Guarantee Period
• Veterinary Reg. No.: Other
• Model NO.: Cefdinir
• CAS No: 91832-40-5
• Mf: C14h13n5o5s2
• Appearance: White to Light Yellow Crystalline Powder
• Grade Standard: Medicine Grade
• Shelf Life: 2 Years
• Transport Package: Bag, Carton, Drum
• Specification: 25kg/drum
• Trademark: Arshine
• Origin: China
• HS Code: 2941905990
• Production Capacity: 200 Tons/Year

Product Description

Pharmaceutical API Veterinary Raw Material CAS91832-40-5 Cefdinir

Cefdinir (Omnicef) is a semi-synthetic, broad-spectrum antibiotic, which is proved to be effective for common bacterial infections of the ear, sinus, throat, and skin.Target: AntibacterialCefdinir is a third generation oral cephalosporin antibiotic. Cefdinir (Omnicef) is a semi-synthetic, broad-spectrum antibiotic in the third generation of the cephalosporin class, which is proved to be effective for common bacterial infections of the ear, sinus, throat, and skin. It can be used to treat infections caused by several Gram-negative and Gram-positive bacteria. It is available in US as Omnicef by Abbott Laboratories and in India as Cednir by Abbott, Kefnir by Glenmark and Cefdiel by Ranbaxy. As of 2008, cefdinir was the highest-selling cephalosporin antibiotic in the United States, with more than US$585 million in retail sales of its generic versions alone.Cefdinir, a new oral 2-amino-5-thiazolyl cephalosporin, inhibited the luminol-amplified chemiluminescence (LACL) response of human neutrophils stimulated by PMA but not opsonized zymosan, in a concentration-dependent but not time-dependent manner. The LACL response to opsonized zymosan in cytochalasin B-treated neutrophils was, however, inhibited by cefdinir. Furthermore, cefdinir inhibited LACL generation in cell-free systems consisting of H2O2, NaI, and either horseradish peroxidase or a myeloperoxidase-containing neutrophil extract. Orthodianisidine oxidation in these two acellular systems was inhibited by cefdinir.

ITEMS	STANDARDS	RESULTS
Appearance	White or off-white crystalline powder	Off-white crystalline powder
Identification	By IR	Complies
	RT under chirality should complies	Complies
	Chloride: it gives a reaction of chloride	Complies
Water	3.0%~4.5%	3.4%
Melting Point	198.0~202.0ºC	199.8~200.5ºC
Residue on Ignition	≤0.2%	0.08%
Heavy Metals	≤10ppm	Complies
Related Substances	Individual Impurities:≤0.5%	0.15%
	Total Impurities:≤1.0%	0.22%
Residual Solvent	Dichloromethane ≤0.06%	0.0066%
	Acetone ≤0.5%	0.015%
	Ethyl acetate ≤0.5%	0.0013%
E.E	≥99.0%	99.6%
Assay (on dry basis)	98.0%~102.0%	101.2%