Pharmaceutical Intermediate CAS117704-25-3 Veterinary Raw Material Pure Doramectin powder
Product Name: Doramectin
Appearance: White powder
Purity: 99%
CAS No.: 117704-25-3
EINECS No.: 241-154-0
Molecular Formula: C50H74O14
Molecular weight: 899.11
Doramectin is used for the treatment and control of internal parasitosis (gastrointestinal and pulmonary nematodes), ticks and mange (and other ectoparasites).Doramectin is a derivative of ivermectin.Its spectrum includes:Haemonchus spp.,Ostertagia spp.,Trichostrongylusspp.,Cooperia spp.,Oesophagostomum spp.,Dictyocaulus viviparus,Dermatobia hominis,Boophilus microplus,Psoroptes bovis,among many other internal and external parasites.Doramectin is available in 2 dosage forms: as aninjection and as a 5 mg/ml topical solution.
| Items |
Specification |
Results |
| Appearance |
White crystalline powder |
pass |
| Identification |
HPLC: the retention time of major peak of test solution should correspond to that of reference solution. |
conform |
| IR: Sample spectrum corresponds to that of standard spectrum. |
conform |
| Appearance of solution |
The solution is clear and not more intensely colored than reference solution BY6. |
conform |
| Related substance |
Avermectin: NMT2.0% |
0.41% |
| Total impurities: NMT5.0% |
2.57% |
| Residual solvents |
Ethanol:NMT30000ppm |
15500ppm |
| Acetone:NMT5000ppm |
5ppm |
| BHT |
NMT2000ppm |
43ppm |
| Sulphate ash |
NMT0.1% |
0.03% |
| Water |
NMT3.0% |
1.6% |
| Heavy metal |
NMT20ppm |
20ppm |
| Assay |
≥95.0% |
99.1% |
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